The Classical Hematologic Examination, known by the acronym CHE, is a tool used to help doctors diagnose certain diseases in patients. Early diagnosis of certain infections, bleeding disorders, or immune disorders can help doctors quickly and accurately determine the most appropriate treatment plan.
CHE tests include a panel of basic reagents that can help in the diagnosis of various conditions, including infections, hereditary diseases, immune disorders, and cancer. These tests are important for proper diagnosis and treatment and may benefit from early detection and appropriate treatment. This discussion will detail some of the common basic CHE reagents and their role in diagnosing different disorders.
What are the common basic reagents used in hematological examination?
The common CHE panel is usually composed of a complete blood count, a coagulation analysis, an extraction of renal function, a CSF parameter, and separate protein electrophoresis. A complete blood count (CBC) is used to measure the quantity and quality of red blood cells, low red blood cell counts (anemia), white blood cells (infections, autoimmune diseases, inflammatory processes), and platelets (bleeding).
The clotting test is used to detect clotting disorders, such as a tendency to clot and a tendency to bleed. Results of kidney function help evaluate kidney problems and include creatinine and blood urea as well as urinary metabolites. Cerebrospinal fluid is used to look for signs of central nervous system infections and abnormal fluid composition in the central nervous system.
Finally, electrophoresis can measure protein levels and detect specific tumor markers, such as alpha-fetoprotein, the polypeptide capsule of the pancreas, and cancer-specific antigens. This procedure occupies an important place in the analyzes, given its importance in the diagnosis and the complexity of its realization.
What is the standard hematology examination used for?
CHE is also used to evaluate changes in bone marrow function. Peripheral blood usually provides inaccurate information about bone marrow behavior. For this reason, more specific studies are needed to obtain a more accurate portrait of bone marrow activity. Clinical studies, as well as a bone marrow biopsy, are useful for evaluating the bone marrow’s response to treatments and for diagnosing hematological conditions.
It is also used to evaluate the immune response. The results can help doctors determine the presence or absence of normal immune response as well as the presence or absence of immune deficiencies. These measurements can be specific to viruses, bacteria, allergens, foods, drugs, and toxins. Abnormal levels of antibodies and other markers may indicate abnormal immune responses and can help doctors identify autoimmune disorders and recommend appropriate treatment.
Why is a classic hematological examination important?
In addition to the basic reagents, many other tests can be done during CHE. These tests vary by patient and condition or disease. For example, liver tests, lipid tests, and blood glucose tests may be ordered for patients who have an increased risk of cardiovascular disease. Folate and vitamin B12 levels can also be measured to detect iron and vitamin B12 deficiency anemia.
Levels of calcium and magnesium, which are used to evaluate diseases such as osteoporosis, can also be measured. In conclusion, the panel of classic basic hematological examination reagents is a useful tool for the diagnosis of infections, hereditary diseases, immune disorders and cancer. CHE is also used to evaluate bone marrow function, immune response, and changes in lipids and metabolites.
The results provide important information that can help the doctor determine the best treatment for the patient quickly and accurately; given the number of diseases, these results can at least indicate what the person does not have. Also, with the help of these tests, doctors can detect cancer early, increasing the likelihood of successful diagnosis and treatment.
The classic hematological examination with the Kalstein analyzers
Kalstein hematology analyzers. Several models are available for sale, some are automated, with various calibration forms and the possibility of analyzing a sample every two minutes. Please refer to the manufacturer’s website at HERE and HERE for information on the purchase and pricing of all equipment.