The use of cytostatic and cytotoxic agents has demonstrated sufficient scientific evidence for carcinogenic, mutagenic and teratogenic effects in humans. The danger exposed to these agents is directed towards the patients who receive the therapeutic doses, but also, there is an important risk of exposure to workers who handle, administer and store these drugs. However, due to the toxicity of cytostatic agents, measures should be taken to reduce exposure to these agents.

Therefore, the potential health risk for healthcare personnel in contact with cytostatic compounds can be controlled through a combination of industrial hygiene actions and controls, personal protective techniques and clothing and appropriate working practices. It is recommended to work in cytotoxic safety cabins with laminar air flow, in charge of guaranteeing protection by the worker and maintaining the sterility of the product.

Cytotoxic Safety Cabinets

The fundamental participation of the cockpit designed for the handling of potentially dangerous drugs, is the cytotoxic safety cabinets, providing protection for the user, and the environment. Because cytotoxic drugs cannot be handled by chemical decontamination, they should be used in safety cabinets with built-in characteristics ideal for:

• To face challenges in the preparation of cytotoxic medicinal products.
• Preserve the maximum degree of cleanliness within the working area, affirming the best possible level of safety, for the patient and cleanliness for the product.
• To contribute to the highest level of safety at work, to protect the user from hazardous components used in cytotoxic medicinal products.
• Respond to the highest possible levels of environmental, operator and product protection.

In addition, it provides easy removal of contaminated filters and sterilization of all contaminated areas without compromising safety, with HEPA filters located directly below the work area, which prevent exposure of users and the environment to potential hazards.

Recommendations for Use

The protocol is to prevent risks arising from inadequate handling or administration of antineoplastic drugs, so the following recommendations are suggested:

• Wear disposable latex surgical gloves, reinforced at the finger area. Polyvinyl chloride (PVC) gloves should not be used as some types are permeable to certain preparations, nor should talc gloves as they attract cytostatic particles.
• Gloves should be changed routinely approximately every half hour when working continuously with these agents.
• The use of gloves should never be a substitute for washing hands.
• For users, protective clothing should be worn for all procedures including preparation and disposal of cytotoxic agents.
• Wear respiratory protection masks in case of spills and in areas where there is no biological safety cabinets.

It should be noted that personnel working with cytotoxic agents must receive special training, since access to the preparation area must be limited for the handling of these compounds, and regular control of equipment ensures compliance with established working methods.

Cytotoxic Safety Bells Brand Kalstein

At Kalstein, we are able to meet the demands of our users in the selection of laboratory equipment. We offer you, the Cytotoxic Safety Campaigns, corresponding to the YR series, where the unique demands of handling and preparing cytotoxic drugs for use in chemotherapy require a specialized cabinet, which has attractive features, such as:

• High quality stainless steel. 253.7 nanometer emission for most.
• Efficient decontamination.
• Front window bag inlet and outlet bag filter.
• Motorized, two-layer laminated hardened PVC bag can ensure the safety of the.
• glass > 5mm, anti UV personal and environmental, and make.
• The replacement process is convenient and fast.
• Armrest, formalin fumigation sterilizer, infrared sterilizer, air flow tester, PVC duct.

To learn more about our products, visit HERE At Kalstein, as manufacturers, we provide all the advice our customers need, so that their purchase is ideal, and at excellent prices. Come visit us at HERE