For 60 days a group of researchers from Columbia University in New York City were creating a heart muscle with stem cells to understand and solve some of the more complex heart diseases that neither drugs nor surgeries had managed to solve. This symbolizes one of the most significant advances in science and medicine in recent years, assuming a manufacturing with cells, previously seen as impossible.
This tissue will allow you to study in depth how the cardiac muscles react to the diversity of diseases present today, and how they can be controlled through appropriate medication that, first of all, because they do not have complete knowledge of the coming reactions after consuming a drug. , the doctors kept to the margin and the expectation of if there were mechanisms capable of improving the pathologies related to the heart and its arteries.
Many laboratories around the world had invested in projects that could generate this tissue; however, none had been successful. The biomedical physicians of Columbia used cardiomyocytes derived from iPS until an exact answer was obtained. Stem cells are characterized by being able to become different types of cells. However, human cells stop doing it when they acquire their maturity, so they do not change its structure. On the other hand, there are induced pluripotent cells which come from an adult, so they have been induced in a period of stem cells.
In this case, a period of electromechanical conditioning was applied, where they were daily increasing contractions by electricity. As a result, each day the developing muscle had to work harder and harder to keep functioning, just as it happens with a heart of its own. The maturation of cells was much faster than they imagined, taking them to the desired point in only four weeks of processing.