Importance in the manufacture of drugs against lupus with the use of the Analytical Balance

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Lupus is an autoimmune disease in which defense cells of the immune system attack the body’s own cellular structures and cause inflammatory changes in various organs of the body. Today, despite advances in medicine, it is not known why this disease is triggered. According to autoimmune theory, lupus is caused by the body fighting itself. However, triggers such as stress, viruses, active hormonal phases, UV light, and some drugs can be mentioned. Additionally, there are different types of lupus, the most common being the first ones on the list:

  • Cutaneous lupus erythematosus (CSF).
  • Systemic lupus erythematosus (SLE).
  • Drug-induced lupus erythematosus (DILE).
  • Neonatal lupus erythematosus (NLE).

What are the most common symptoms of lupus?

The symptoms and discomfort that occur depend mainly on the form of the disease, how the disease progresses, and the overall severity of lupus. For example, cutaneous lupus erythematosus affects mainly the skin and causes inflammatory changes in different parts of the body, whereas systemic lupus erythematosus also affects internal organs and can lead to serious secondary diseases. In general, some of the symptoms that people with this disease have include the following:

  • Fever occurs in about one third of patients, accompanied by fatigue and fatigue. Weight loss and chills are also possible.
  • Skin, flushed cheeks, and rashes on certain parts of the body.
  • Vascular problems.
  • Joint pain or swelling.
  • Blood, changes in the count of all types of blood cells.
  • Coagulation, increased thrombosis.
  • Kidneys, decreased kidney function.
  • Lungs, inflammation of the pleura.
  • Heart, pericarditis occurs.
  • Nervous system damage.

What treatments are available for lupus?

Drug treatment must be carefully tailored to the individual course of the disease. In milder cases, such as joint pain, a nonsteroidal anti-inflammatory drug (NSAID) may be sufficient. Special ointments help prevent the skin from becoming red. If joints and skin are affected at the same time and more severely, antimalarials are effective in fighting symptoms. Cortisone preparations are also commonly used, always in combination with immunosuppressants for severe internal organ infestation. Drug treatment requires regular urine and blood tests. In summary, treatment of this disease requires at least four types of drugs:

  • Steroidal anti-inflammatory.
  • Non-steroidal anti-inflammatory drugs.
  • Antimalarials.
  • Immunosuppressants.

The use of these drugs, the doses, and the total duration of treatment depend on how severe the lupus disorder is. Similarly, one or two or all of these drugs may be given, so medical surveillance during the disease is mandatory. Therefore, the quality of the medication, at least in the required dose, during key moments of treatment, makes it necessary to use measuring instruments that ensure that the patient is being given the prescribed dose, and it is in this section that the analytical balance, provides that key measurement.

Importance of the analytical balance in the manufacture of medicines

Pharmacokinetics allow dose titration to be established in order to maintain the optimal concentration of the drug in the blood, so that the expected effects of treatment can be observed. In this sense, measuring the exact dosage of drugs is only possible with the help of the analytical balance, since it can record with high accuracy and accuracy, very small amounts of bioactive substances, used in the different phases of a treatment. Therefore, the analytical balance is an extremely important instrument, since it gives certainty to the treating physician of the dose administered to the patient of the prescribed drug.

Why buy an analytical scale from the manufacturer Kalstein to make medicines?

The pharmaceutical industry is subject to rigorous controls that monitor the quality of the products derived from it, and one of these controls is related to the exact content of the active ingredient of the formulation, which can only be measured with the support of an analytical balance, the one provided by the manufacturer Kalstein being one of the best. The company makes available (price and/or purchase) the models YR053501 // YR053502, which have an electromagnetic sensor for mass measurement, different units for measurement expression, protection against air fluctuations, short stabilization time and the function of tarar. For images and additional information of these scales, please refer to HERE 

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